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CS-W001157 4
Total: USD 88.00

4-(4-Nitrophenyl)piperidine

  • CAS No. 26905-03-3

  • Cat. No. CS-0157626
  • Purity≥95%
  • MDL No.MFCD06804549

*For research and further manufacturing use only, not for direct human use.

4-(4-Nitrophenyl)piperidine|CS-0157626

Structure of 26905-03-3

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General Information

  • CAS No. 26905-03-3
  • Cat. No. CS-0157626
  • Purity ≥95%
  • MDL No. MFCD06804549
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂O₂
  • Molecular Weight 206.24
  • Synonym(s) 4-(4-NITRO-PHENYL)-PIPERIDINE
  • SMILES C1=C(C=CC(=C1)[N+](=O)[O-])C2CCNCC2

Description

4-(4-Nitrophenyl)piperidine is a bench-stable, electron-deficient piperidine derivative featuring a para-nitro aryl group that enhances reactivity in coupling processes. This structural motif enables efficient integration into pharmaceutical intermediates and functional materials, offering predictable behavior under standard conditions.

Application

4-(4-Nitrophenyl)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of diverse heterocyclic scaffolds. Its robust piperidine core exhibits favorable solubility and stability under standard synthetic conditions, while the para-nitrophenyl group provides a handle for subsequent transformations such as reduction to aniline derivatives or Suzuki coupling. The molecule functions effectively in multi-step synthesis workflows, offering predictable reactivity and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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Computational Chemistry Data

  • TPSA   55.17
  • LogP   2.0618
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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