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CS-W001157 4
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6-Bromoimidazo[1,2-a]pyrazin-2-amine

  • CAS No. 1103861-38-6

  • Cat. No. CS-0084720
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromoimidazo[1,2-a]pyrazin-2-amine|CS-0084720

Structure of 1103861-38-6

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General Information

  • CAS No. 1103861-38-6
  • Cat. No. CS-0084720
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrN₄
  • Molecular Weight 213.03
  • Synonym(s) Pentanedioic acid,6-bromohexyl hexyl ester
  • SMILES NC1=CN2C(C=NC(Br)=C2)=N1

Description

6-Bromoimidazo[1,2-a]pyrazin-2-amine features a fused heterocyclic core bearing a bromine atom at the 6-position and an amine functionality at the 2-position. This combination enables direct incorporation into cross-coupling reactions and facilitates downstream derivatization in medicinal chemistry campaigns. The molecule exhibits good stability under standard bench conditions and solubility in common organic solvents.

Application

6-Bromoimidazo[1,2-a]pyrazin-2-amine serves as a versatile heterocyclic building block for medicinal chemistry and catalyst development. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the imidazopyrazine core provides structural rigidity and hydrogen-bonding capacity. The compound exhibits excellent bench stability and facilitates efficient functionalization in standard synthetic workflows, making it well-suited for the construction of complex nitrogen-containing scaffolds in API discovery and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   56.21
  • LogP   1.074
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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