Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate

  • CAS No. 1095822-17-5

  • Cat. No. CS-0048911
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate|CS-0048911

Structure of 1095822-17-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1095822-17-5
  • Cat. No. CS-0048911
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O₂
  • Molecular Weight 177.16
  • Synonym(s) 7H-Pyrrolo[2,3-d]pyrimidine-4-carboxylic acid, methyl ester
  • SMILES COC(=O)C1=C2C=CNC2=NC=N1

Description

Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate is a heterocyclic building block featuring a fused pyrrole-pyrimidine core with a methyl ester at the C4 position. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents due to its planar structure and hydrogen-bonding capacity. The ester group enables further derivatization under standard conditions.

Application

Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate serves as a versatile building block for the synthesis of purine-derived scaffolds and kinase inhibitor candidates. Its pyrrolopyrimidine core exhibits excellent stability under standard reaction conditions and tolerates a range of functional groups. The ester moiety enables facile derivatization via hydrolysis or nucleophilic substitution, facilitating access to diverse analogs in medicinal chemistry campaigns.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      4-Iodo-7H-pyrrolo[2,3-d]pyrimidine|CS-0050827
      1100318-96-4
    • null|null
      201230-82-2
    • ~89%
    • In-stock
      Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate|CS-0048911
      1095822-17-5

    References

    • LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCÈ VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRÍGUEZ GARRIDO, Antonio, David; CARCELLER GONZÁLEZ, Elena; SALAS SOLANA, Jordi Patent: WO2013/37960 A1, 2013 ; Location in patent: Page/Page column 75 ;
  • Route2
    • null|null
      67-56-1
    • null|null
      201230-82-2
    • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Tofacitinib Impurity|CS-0213936
      3680-69-1
    • ~44%
    • In-stock
      Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate|CS-0048911
      1095822-17-5

    References

    • Sunesis Pharmaceuticals, Inc Patent: US2009/5359 A1, 2009 ; Location in patent: Page/Page column 16; 24 ; US 20090005359 A1
  • Route3
    • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Tofacitinib Impurity|CS-0213936
      3680-69-1
    • ~%
    • In-stock
      Methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate|CS-0048911
      1095822-17-5

    References

    • LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCÈ VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRÍGUEZ GARRIDO, Antonio, David; CARCELLER GONZÁLEZ, Elena; SALAS SOLANA, Jordi Patent: WO2013/37960 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   67.87
  • LogP   0.7445
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1095822-17-5 sigma1095822-17-5 manufacturer1095822-17-5 price1095822-17-5 structure1095822-17-5 SDSbuy 1095822-17-51095822-17-5 supplier1095822-17-5 uses1095822-17-5 molecular weightprice of 1095822-17-51095822-17-5 chemical name formula of 1095822-17-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label