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Structure of 1095539-84-6
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6-Bromo-1,3-dimethyl-1H-indazole is a bench-stable heterocyclic scaffold featuring a brominated indazole core with methyl groups at positions 1 and 3. This configuration imparts enhanced solubility and electronic tunability, enabling direct coupling in palladium-catalyzed cross-coupling reactions. The molecule serves as a key building block for bioactive compound synthesis, particularly in medicinal chemistry and materials science applications.
6-Bromo-1,3-dimethyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for C–C bond formation. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the methyl groups enhance solubility and metabolic stability. The indazole core offers a rigid, hydrogen-bond-capable scaffold suitable for targeted protein inhibition. This compound exhibits excellent bench stability and is readily purified by flash chromatography or recrystallization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: