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Structure of 1089695-61-3
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2-(Difluoromethoxy)acetic acid features a difluoromethoxy group attached to a carboxylic acid moiety, delivering enhanced lipophilicity and metabolic stability. This configuration enables robust integration into bioactive molecules, particularly in medicinal chemistry scaffolds requiring improved membrane permeability and resistance to enzymatic degradation.
2-(Difluoromethoxy)acetic acid serves as a valuable building block for fluorinated bioactive molecules, enabling direct incorporation of the difluoromethoxy group into pharmaceutical and agrochemical scaffolds. Its stability under standard synthetic conditions and compatibility with common coupling reactions facilitate efficient derivatization. The carboxylic acid functionality supports straightforward functionalization via esterification, amide formation, or metalation, making it a practical reagent for medicinal chemistry campaigns targeting enhanced metabolic stability and membrane permeability.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: