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tert-Butyl (2-((2-aminoquinolin-4-yl)oxy)ethyl)carbamate

  • CAS No. 1085412-36-7

  • Cat. No. CS-0009315
  • Purity≥98%
  • MDL No.MFCD24466553

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-((2-aminoquinolin-4-yl)oxy)ethyl)carbamate|CS-0009315

Structure of 1085412-36-7

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General Information

  • CAS No. 1085412-36-7
  • Cat. No. CS-0009315
  • Purity ≥98%
  • MDL No. MFCD24466553
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₁N₃O₃
  • Molecular Weight 303.36
  • Synonym(s) tert-butyl 2-(2-aMinoquinolin-4-yloxy)ethylcarbaMate
  • SMILES O=C(OC(C)(C)C)NCCOC1=CC(N)=NC2=CC=CC=C12

Description

tert-Butyl (2-((2-aminoquinolin-4-yl)oxy)ethyl)carbamate is a bench-stable, moisture-tolerant protecting group derivative featuring a quinoline scaffold with a pendant alkoxy-functionalized side chain. This compound integrates seamlessly into synthetic sequences requiring selective amino and ether functionalities, enabling efficient downstream transformations in medicinal chemistry and target-oriented synthesis.

Application

tert-Butyl (2-((2-aminoquinolin-4-yl)oxy)ethyl)carbamate serves as a versatile building block for the synthesis of quinoline-based pharmaceutical intermediates. The protected amine and ether functionalities enable orthogonal reactivity in multistep syntheses, while the tert-butyl carbamate group offers excellent bench stability and ease of removal under mild acidic conditions. It functions effectively in coupling reactions and heterocyclic scaffold elaboration, supporting efficient access to bioactive molecules in medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   86.47
  • LogP   2.7205
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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