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CS-W001157 4
Total: USD 88.00

Dimethyl malonate

  • CAS No. 108-59-8

  • Cat. No. CS-0019394
  • Purity≥98%
  • MDL No.MFCD00008460

*For research and further manufacturing use only, not for direct human use.

Dimethyl malonate|CS-0019394

Structure of 108-59-8

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General Information

  • CAS No. 108-59-8
  • Cat. No. CS-0019394
  • Purity ≥98%
  • MDL No. MFCD00008460
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₄
  • Molecular Weight 132.11
  • Synonym(s) None
  • SMILES O=C(OC)CC(OC)=O

Description

Dimethyl malonate undergoes enantioselective palladium-catalyzed allylic substitution reaction with 1,3-diphenylprop-2-enyl acetate to yield diastereomeric pure thienylpyridines.Dimethyl malonate was used in gold catalyzed oxidative esterification of glycerol, 1,2-propanediol and 1,3-propanediol.

Synthesis

  • Route1
    • null|null
      96-34-4
    • ~89%
    • In-stock
      Dimethyl malonate|CS-0019394
      108-59-8

    References

    • US4399300 A1, ;
  • Route2
    • null|null
      67-56-1
    • null|null
      141-82-2
    • ~99%
    • In-stock
      Dimethyl malonate|CS-0019394
      108-59-8

    References

    • Analytical Chemistry, , vol. 76, # 16 p. 4765 - 4778
  • Route3
    • null|null
      74-87-3
    • In-stock
      Sodium malonate|CS-0328770
      141-95-7
    • ~69%
    • In-stock
      Dimethyl malonate|CS-0019394
      108-59-8

    References

    • US6350898 B1, ; Example 11 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   -0.2775
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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