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CS-W001157 4
Total: USD 88.00

2,6-Dimethylpyrazine

  • CAS No. 108-50-9

  • Cat. No. CS-W021530
  • Purity≥98%
  • MDL No.MFCD00006148

*For research and further manufacturing use only, not for direct human use.

2,6-Dimethylpyrazine|CS-W021530

Structure of 108-50-9

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General Information

  • CAS No. 108-50-9
  • Cat. No. CS-W021530
  • Purity ≥98%
  • MDL No. MFCD00006148
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂
  • Molecular Weight 108.14
  • Synonym(s) None
  • SMILES CC1=CN=CC(C)=N1

Description

2-(4-(2-aminoethyl)piperazin-1-yl)ethanamine is a piperazine with two N-ethanamine groups. This type of molecule may be used to build drug molecules or design novel ionizable aminolipid head groups for lipid nanoparticles.

Application

2,6-Dimethylpyrazine serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling the construction of bioactive scaffolds and flavor/fragrance compounds. Its stability under standard reaction conditions and tolerance to diverse functional groups facilitate efficient derivatization. The molecule functions as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly where pyrazine-based ring systems contribute to metabolic stability and target binding affinity.

Synthesis

  • Route1
    • null|null
      1201003-56-6
    • ~75%
    • In-stock
      2,6-Dimethylpyrazine|CS-W021530
      108-50-9

    References

    • Rizk, Toni; Bilodeau, Eric J.-F.; Beauchemin, Andre M. Angewandte Chemie - International Edition, 2009 , vol. 48, # 44 p. 8325 - 8327
  • Route2
    • In-stock
      2,6-Dichloropyrazine|CS-W010976
      4774-14-5
    • null|null
      676-58-4
    • ~49%
    • In-stock
      2,6-Dimethylpyrazine|CS-W021530
      108-50-9

    References

    • Dickschat, Jeroen S.; Reichenbach, Hans; Wagner-Doebler, Irene; Schulz, Stefan European Journal of Organic Chemistry, 2005 , # 19 p. 4141 - 4153
  • Route3
    • null|null
      133129-19-8
    • ~%
    • In-stock
      2,6-Dimethylpyrazine|CS-W021530
      108-50-9

    References

    • Journal of Organic Chemistry, , vol. 56, # 8 p. 2605 - 2606

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228-H302-H315-H318-H335
Precautionary Statements : P210-P240-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.09344
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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