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CS-W001157 4
Total: USD 88.00

Ligustrazine

  • CAS No. 1124-11-4

  • Cat. No. CS-W023183
  • Purity≥98%
  • MDL No.MFCD00006146

*For research and further manufacturing use only, not for direct human use.

Ligustrazine|CS-W023183

Structure of 1124-11-4

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General Information

  • CAS No. 1124-11-4
  • Cat. No. CS-W023183
  • Purity ≥98%
  • MDL No. MFCD00006146
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight None
  • Synonym(s) Chuanxiongzine; Tetramethylpyrazine
  • SMILES CC1=C(C)N=C(C)C(C)=N1

Description

2,3,5,6-Tetramethylpyrazine has been isolated from Ephedra sinica. It is useful in the treatment of several disorders such as asthma, heart failure, rhinitis and urinary incontinence. It is a flavor ingredient of tobacco. It forms cocrystal with 4-hydroxybenzoic acid which exhibits supramolecular synthon polymorphism.

Synthesis

  • Route1

    References

    • Chiba, Toshiro; Sakagami, Hirotoshi; Murata, Miki; Okimoto, Mitsuhiro Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6764 - 6770
  • Route2
    • null|null
      513-86-0
    • ~43%
    • In-stock
      Ligustrazine|CS-W023183
      1124-11-4

    References

    • Shu, Chi-Kuen; Lawrence, Brian M. Journal of Agricultural and Food Chemistry, 1995 , vol. 43, # 11 p. 2922 - 2924
  • Route3
    • null|null
      17117-97-4
    • ~%
    • In-stock
      Ligustrazine|CS-W023183
      1124-11-4

    References

    • Journal of the American Chemical Society, , vol. 55, p. 4167,4169, 4173

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H335-H318
Precautionary Statements : P270-P280-P261-P305+P351+P338-P310-P301+P312-P405-P403+P233-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.71028
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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