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Structure of 1072951-45-1
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This boronate moiety integrates a 5-fluoroquinolin-8-yl scaffold, offering enhanced stability and reactivity in cross-coupling transformations. The electron-deficient quinoline core enables efficient palladium-catalyzed coupling under standard conditions, while the fluorine substituent modulates electronic properties and improves solubility in organic media.
(5-Fluoroquinolin-8-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation with aryl halides and triflates. The quinoline scaffold provides enhanced metabolic stability and favorable electronic properties for medicinal chemistry applications. Its bench-stable boronic acid functionality facilitates straightforward handling, purification, and integration into diverse synthetic sequences, including the construction of biologically active heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: