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Structure of 1065114-27-3
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tert-Butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a sterically hindered tert-butyl ester and two chlorine substituents at electron-deficient positions. This configuration enables direct coupling in late-stage functionalization, facilitating rapid access to bioactive pyrimidopyrazine scaffolds under standard conditions.
tert-Butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. The dichloro substitution pattern enables sequential functionalization via nucleophilic displacement, while the tert-butyl ester group offers stability and ease of removal under mild acidic conditions. Its well-defined reactivity profile supports efficient access to diverse pyrimidoazepine derivatives in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: