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Structure of 1064783-29-4
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5-Chloro-3-fluoro-2-nitropyridine is a fluorinated, chlorinated pyridine derivative featuring a nitro group at the 2-position. This electron-deficient heterocycle integrates seamlessly into cross-coupling reactions and serves as a key intermediate in medicinal chemistry. The ortho-nitro group enables direct functionalization, while the flanking halogens facilitate palladium-catalyzed transformations under standard conditions.
5-Chloro-3-fluoro-2-nitropyridine serves as a versatile building block for the synthesis of functionalized pyridine derivatives, enabling direct substitution at C5 and C3 via palladium-catalyzed cross-coupling or nucleophilic aromatic substitution. Its ortho-difunctionalized structure provides high reactivity and selectivity in late-stage diversification, facilitating access to complex heterocyclic scaffolds relevant to medicinal chemistry. The molecule exhibits excellent bench stability and compatibility with standard purification techniques.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: