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CS-W001157 4
Total: USD 88.00

H-Ser-Otbu.HCl

  • CAS No. 106402-41-9

  • Cat. No. CS-W005138
  • Purity≥97%
  • MDL No.MFCD00270570

*For research and further manufacturing use only, not for direct human use.

H-Ser-Otbu.HCl|CS-W005138

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General Information

  • CAS No. 106402-41-9
  • Cat. No. CS-W005138
  • Purity ≥97%
  • MDL No. MFCD00270570
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆ClNO₃
  • Molecular Weight 197.66
  • Synonym(s) H-Ser-OtBu · HCl
  • SMILES O=C(OC(C)(C)C)[C@@H](N)CO.[H]Cl

Description

H-Ser-Otbu·HCl features a protected serine side chain with a bulky tert-butyl ether group, offering enhanced stability and ease of handling in peptide synthesis. This derivative enables efficient incorporation of serine residues under standard coupling conditions, minimizing epimerization risks while maintaining compatibility with common deprotection protocols.

Application

H-Ser-Otbu·HCl serves as a stable, bench-ready amino acid building block for peptide synthesis, enabling efficient incorporation of serine residues with minimal side reactions. The OtBu protecting group offers high stability under standard coupling conditions and facilitates straightforward deprotection using mild acid. Its hydrochloride salt form enhances solubility and handling, making it ideal for automated and manual synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.0695
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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