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Structure of 106139-15-5
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2-(Pyridyldithio)ethylamine (hydrochloride) features a pyridyl-thiol group that enables selective, reversible conjugation with cysteine residues in proteins. This reagent integrates efficiently into site-specific bioconjugation workflows, offering stable linkage under physiological conditions while maintaining solubility and ease of handling.
2-(Pyridyldithio)ethylamine (hydrochloride) serves as a versatile bifunctional reagent for site-specific conjugation and protein labeling. The pyridyldithio group enables efficient disulfide exchange with thiol-containing biomolecules under mild conditions, while the primary amine facilitates coupling to activated carboxylates or aldehydes. Its hydrochloride salt form enhances solubility and bench stability, simplifying handling in aqueous-based workflows. Functions effectively in antibody-drug conjugate synthesis and bioconjugation protocols requiring orthogonal functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: