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Structure of 1060815-60-2
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2-Bromo-6-chloronicotinaldehyde is a halogenated pyridine aldehyde featuring orthogonal reactivity at the aldehyde and halide sites. This electron-deficient heterocycle integrates readily into cross-coupling cascades and serves as a key building block for bioactive scaffolds in medicinal chemistry.
2-Bromo-6-chloronicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its ortho-halogenated aldehyde functionality offers high reactivity in C–H functionalization and facilitates efficient derivatization under mild conditions. The compound exhibits good bench stability and is compatible with diverse protecting groups, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: