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5-(tert-Butyl) 2-ethyl 6,7-dihydrofuro[3,2-c]pyridine-2,5(4H)-dicarboxylate

  • CAS No. 1060814-36-9

  • Cat. No. CS-0101148
  • Purity≥98%
  • MDL No.MFCD10698557

*For research and further manufacturing use only, not for direct human use.

5-(tert-Butyl) 2-ethyl 6,7-dihydrofuro[3,2-c]pyridine-2,5(4H)-dicarboxylate|CS-0101148

Structure of 1060814-36-9

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General Information

  • CAS No. 1060814-36-9
  • Cat. No. CS-0101148
  • Purity ≥98%
  • MDL No. MFCD10698557
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁NO₅
  • Molecular Weight 295.33
  • Synonym(s) 5-Tert-butyl 2-ethyl 6,7-dihydrofuro[3,2-C]pyridine-2,5(4H)-dicarboxylate
  • SMILES O=C(OCC)C1=CC2=C(CCN(C2)C(OC(C)(C)C)=O)O1

Description

This furo[3,2-c]pyridine derivative features a sterically hindered tert-butyl group and an ethyl substituent that enhance solubility and stability under standard conditions. The dihydrofuro scaffold provides a rigid, electron-rich platform ideal for integration into complex heterocyclic systems.

Application

5-(tert-Butyl) 2-ethyl 6,7-dihydrofuro[3,2-c]pyridine-2,5(4H)-dicarboxylate serves as a versatile heterocyclic building block for the synthesis of furo[3,2-c]pyridine scaffolds. Its dicarboxylate functionality enables selective derivatization under standard conditions, while the tert-butyl and ethyl groups provide steric stability and favorable purification profiles. The molecule exhibits good bench stability and functional group tolerance, facilitating its use in modular synthetic sequences for medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   68.98
  • LogP   2.7495
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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