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tert-Butyl 7-aminoheptanoate

  • CAS No. 105974-64-9

  • Cat. No. CS-0098202
  • Purity≥97%
  • MDL No.MFCD12804784

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 7-aminoheptanoate|CS-0098202

Structure of 105974-64-9

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General Information

  • CAS No. 105974-64-9
  • Cat. No. CS-0098202
  • Purity ≥97%
  • MDL No. MFCD12804784
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₃NO₂
  • Molecular Weight 201.31
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCCCCCN

Description

tert-Butyl 7-aminoheptanoate features a primary amine group flanked by a hydrophobic alkyl chain and a sterically hindered tert-butyl ester, enabling stable incorporation into peptide-like scaffolds. This combination supports efficient coupling reactions under standard conditions while maintaining solubility in common organic solvents.

Application

tert-Butyl 7-aminoheptanoate serves as a versatile amino acid surrogate in peptide and heterocyclic synthesis, enabling efficient access to γ-amino acid derivatives. Its tert-butyl carbamate group provides excellent stability and orthogonal cleavage under mild acidic conditions, facilitating downstream functionalization. The primary amine supports diverse coupling reactions and acts as a key building block for bioactive scaffolds and macrocyclic architectures in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   2.2373
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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