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CS-W001157 4
Total: USD 88.00

4-(Methylamino)benzoic acid

  • CAS No. 10541-83-0

  • Cat. No. CS-0029513
  • Purity≥97%
  • MDL No.MFCD00002535

*For research and further manufacturing use only, not for direct human use.

4-(Methylamino)benzoic acid|CS-0029513

Structure of 10541-83-0

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General Information

  • CAS No. 10541-83-0
  • Cat. No. CS-0029513
  • Purity ≥97%
  • MDL No. MFCD00002535
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) NSC 102506; 4-Methylaminobenzoic acid
  • SMILES O=C(O)C1=CC=C(NC)C=C1

Description

4-(Methylamino)benzoic acid features a para-substituted aromatic core with a methylamino group enhancing electron density and a carboxylic acid moiety enabling derivatization. This combination supports conjugation in bioconjugation workflows and facilitates integration into pharmaceutical scaffolds under standard conditions.

Application

4-(Methylamino)benzoic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both amine and carboxylic acid functionalities for subsequent derivatization. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient peptide and amide synthesis. The ortho-directed substitution pattern supports reliable functionalization in heterocyclic scaffold construction.

Synthesis

  • Route1
    • 4-Aminobenzoic acid Conivaptan Impurity|CS-0213989
      150-13-0
    • null|null
      616-38-6
    • ~74%
    • In-stock
      4-(Methylamino)benzoic acid|CS-0029513
      10541-83-0

    References

    • CONSORZIO INTERUNIVERSITARIO NAZIONALE "LA CHIMICA PER L'AMBIENTE" Patent: US2004/127747 A1, 2004 ; Location in patent: Page 4 ;
  • Route2
    • In-stock
      4-Bromobenzoic acid|CS-W020100
      586-76-5
    • null|null
      74-89-5
    • ~95%
    • In-stock
      4-(Methylamino)benzoic acid|CS-0029513
      10541-83-0

    References

    • Jiao, Jiao; Zhang, Xi-Ru; Chang, Ning-Hui; Wang, Jie; Wei, Jun-Fa; Shi, Xian-Ying; Chen, Zhan-Guo Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1180 - 1183
  • Route3
    • null|null
      74-89-5
    • 4-Chlorobenzoic acid Bezafibrate Impurity|CS-0229800
      74-11-3
    • ~56%
    • In-stock
      4-(Methylamino)benzoic acid|CS-0029513
      10541-83-0

    References

    • Jiao, Jiao; Zhang, Xi-Ru; Chang, Ning-Hui; Wang, Jie; Wei, Jun-Fa; Shi, Xian-Ying; Chen, Zhan-Guo Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1180 - 1183

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.4265
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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