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CS-W001157 4
Total: USD 88.00

Boc-NH-PEG8-CH2CH2NH2

  • CAS No. 1052207-59-6

  • Cat. No. CS-0116306
  • Purity≥98%
  • MDL No.MFCD31656919

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG8-CH2CH2NH2|CS-0116306

Structure of 1052207-59-6

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General Information

  • CAS No. 1052207-59-6
  • Cat. No. CS-0116306
  • Purity ≥98%
  • MDL No. MFCD31656919
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₄₈N₂O₁₀
  • Molecular Weight 512.63
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCN

Description

Boc-NH-PEG8-CH2CH2NH2 features a tert-butoxycarbonyl-protected amine terminus linked to a hydrophilic PEG8 chain, terminating in a primary amine. This bifunctional scaffold enables site-specific conjugation and efficient solubility in aqueous media. The protected amine facilitates controlled deprotection under mild acidic conditions, allowing precise functionalization in peptide synthesis and bioconjugation workflows.

Application

Boc-NH-PEG8-CH₂CH₂NH₂ serves as a versatile bifunctional linker for conjugation and solid-phase synthesis. The Boc-protected amine enables stable storage and selective deprotection, while the distal primary amine facilitates coupling reactions with carboxylic acids or activated esters. The eight-ethylene glycol unit provides enhanced solubility and reduced aggregation, making it ideal for peptide modification, bioconjugation, and the construction of PEGylated scaffolds in medicinal chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   138.19
  • LogP   0.6026
  • H_Acceptors   11
  • H_Donors   2
  • Rotatable_Bonds   26

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