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CS-W001157 4
Total: USD 88.00

sSPhos

  • CAS No. 1049726-96-6

  • Cat. No. CS-0035147
  • Purity≥97%
  • MDL No.MFCD07781994

*For research and further manufacturing use only, not for direct human use.

sSPhos|CS-0035147

Structure of 1049726-96-6

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General Information

  • CAS No. 1049726-96-6
  • Cat. No. CS-0035147
  • Purity ≥97%
  • MDL No. MFCD07781994
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₃₆NaO₆PS
  • Molecular Weight 530.60
  • Synonym(s) Sodium 2'-(dicyclohexylphosphanyl)-2,6-dimethoxy-[1,1'-biphenyl]-3-sulfonate hydrate; Sodium 2'-(dicyclohexylphosphino)-2,6-dimethoxy-[1,1'-biphenyl]-3-sulfonate hydrate
  • SMILES O=S(C1=CC=C(OC)C(C2=C(P(C3CCCCC3)C4CCCCC4)C=CC=C2)=C1OC)(O[Na])=O.O

Application

sSPhos serves as a highly effective, bench-stable phosphine ligand in palladium-catalyzed cross-coupling reactions. Its sterically demanding yet electronically tunable structure enables efficient coupling of challenging substrates, including aryl chlorides and sterically hindered partners. The ligand facilitates catalyst activation, enhances reaction rates, and improves yields across diverse coupling protocols—making it a practical choice for both synthetic and process chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   93.33
  • LogP   5.1075
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   8

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