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Structure of 103862-63-1
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4-Chloro-6-ethoxyquinoline is a bench-stable, electron-deficient quinoline derivative featuring a chloro group at the 4-position and an ethoxy substituent at the 6-position. This combination enhances its utility in transition-metal-catalyzed cross-coupling reactions and as a building block in pharmaceutical synthesis.
4-Chloro-6-ethoxyquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic chlorine site. The ethoxy group enhances solubility and modulates electronic properties, while the quinoline scaffold provides a rigid, planar framework suitable for drug-like molecule development. This compound exhibits excellent bench stability and facilitates straightforward purification, making it ideal for iterative synthesis campaigns in API discovery and process optimization.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: