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CS-W001157 4
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(S)-2-(2-hydroxyethyl)piperidine

  • CAS No. 103639-57-2

  • Cat. No. CS-W019797
  • Purity≥95%
  • MDL No.MFCD08461072

*For research and further manufacturing use only, not for direct human use.

(S)-2-(2-hydroxyethyl)piperidine|CS-W019797

Structure of 103639-57-2

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General Information

  • CAS No. 103639-57-2
  • Cat. No. CS-W019797
  • Purity ≥95%
  • MDL No. MFCD08461072
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO
  • Molecular Weight 129.20
  • Synonym(s) (-)-2-Piperidineethanol; (2S)-2-(2-Hydroxyethyl)piperidine; (S)-2-(2-Hydroxyethyl)piperidine; (S)-2-(Piperidin-2-yl)ethanol; (S)-2-Piperidineethanol
  • SMILES OCC[C@@H]1CCCCN1

Description

(S)-2-(2-hydroxyethyl)piperidine features a chiral piperidine core bearing a hydroxyl-functionalized ethyl side chain, enabling precise stereocontrolled synthesis in medicinal chemistry. This bench-stable, moisture-tolerant scaffold integrates readily into bioactive molecules, offering enhanced solubility and hydrogen-bonding capacity for drug discovery applications.

Synthesis

  • Route1

    References

    • US2008/51579 A1, ; Page/Page column 9 ;
  • Route2
    • In-stock
      2-Piperidineethanol|CS-W001979
      1484-84-0
    • ~%
    • In-stock
      (S)-2-(2-hydroxyethyl)piperidine|CS-W019797
      103639-57-2
    • (R)-2-(Piperidin-2-yl)ethanol|CS-0155252
      68419-38-5

    References

    • Snider, Barry B.; Grabowski, James F. Journal of Organic Chemistry, 2007 , vol. 72, # 3 p. 1039 - 1042

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3263
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.5109
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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