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CS-W001157 4
Total: USD 88.00

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride

  • CAS No. 103614-40-0

  • Cat. No. CS-W006595
  • Purity≥97%
  • MDL No.MFCD08457605
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride|CS-W006595

Structure of 103614-40-0

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Description

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride is a chiral building block featuring a stereodefined (S)-configuration at the alpha carbon. This bench-stable derivative integrates a protected amino group flanked by a tert-butyl ester, enabling straightforward deprotection and coupling in peptide synthesis. The hydrochloride salt enhances solubility and handling under standard conditions.

Application

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride serves as a chiral building block for synthesizing bioactive amines and peptidomimetics. Its stability, ease of handling, and compatibility with standard amine deprotection protocols enable efficient access to (S)-α-methylamino acid derivatives. Functions as a key intermediate in the construction of heterocyclic scaffolds and medicinally relevant motifs requiring stereocontrolled side-chain introduction.

General Information

  • CAS No. 103614-40-0
  • Cat. No. CS-W006595
  • Purity ≥97%
  • MDL No. MFCD08457605
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈ClNO₂
  • Molecular Weight 195.69
  • Synonym(s) N-METHYL-L-ALANINE T-BUTYL ESTER HYDROCHLORIDE
  • SMILES C[C@@H](C(OC(C)(C)C)=O)NC.Cl

Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.3578
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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