H-N-Me-DL-Ala-OH

Name: H-N-Me-DL-Ala-OH
Brand: ChemScene
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CAS No. 600-21-5
Cat. No. CS-W011307
Purity≥98%
MDL No.MFCD00063136

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 600-21-5

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Description

H-N-Me-DL-Ala-OH is a synthetic dipeptide derivative featuring a methylated alanine residue, offering enhanced metabolic stability and improved membrane permeability. This modified amino acid scaffold facilitates efficient incorporation into peptide-based therapeutics and serves as a key building block in bioconjugation workflows.

Application

H-N-Me-DL-Ala-OH serves as a versatile building block in peptide synthesis, offering enhanced solubility and stability compared to native alanine. The N-methyl group reduces backbone hydrogen bonding, minimizing aggregation and facilitating coupling efficiency in solid-phase protocols. Its DL-diastereomeric form provides flexibility for exploring conformational diversity in peptidomimetic design, while the terminal amine and carboxylic acid enable straightforward conjugation and derivatization in standard synthetic workflows.

General Information

CAS No. 600-21-5
Cat. No. CS-W011307
Purity ≥98%
MDL No. MFCD00063136
Storage polypeptide, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₉NO₂
Molecular Weight 103.12
Synonym(s) N-Methyl-DL-alanine
SMILES CC(NC)C(O)=O

Computational Chemistry Data

TPSA 49.33
LogP -0.3211
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Biologically-modified Amino Acids

Key Words

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H-N-Me-DL-Ala-OH

CAS No. 600-21-5

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