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CS-W001157 4
Total: USD 88.00

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride

  • CAS No. 103614-40-0

  • Cat. No. CS-W006595
  • Purity≥97%
  • MDL No.MFCD08457605

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride|CS-W006595

Structure of 103614-40-0

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General Information

  • CAS No. 103614-40-0
  • Cat. No. CS-W006595
  • Purity ≥97%
  • MDL No. MFCD08457605
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈ClNO₂
  • Molecular Weight 195.69
  • Synonym(s) N-METHYL-L-ALANINE T-BUTYL ESTER HYDROCHLORIDE
  • SMILES C[C@@H](C(OC(C)(C)C)=O)NC.Cl

Description

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride is a chiral building block featuring a stereodefined (S)-configuration at the alpha carbon. This bench-stable derivative integrates a protected amino group flanked by a tert-butyl ester, enabling straightforward deprotection and coupling in peptide synthesis. The hydrochloride salt enhances solubility and handling under standard conditions.

Application

(S)-tert-Butyl 2-(methylamino)propanoate hydrochloride serves as a chiral building block for synthesizing bioactive amines and peptidomimetics. Its stability, ease of handling, and compatibility with standard amine deprotection protocols enable efficient access to (S)-α-methylamino acid derivatives. Functions as a key intermediate in the construction of heterocyclic scaffolds and medicinally relevant motifs requiring stereocontrolled side-chain introduction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.3578
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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