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CS-W001157 4
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(S)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid

  • CAS No. 1033713-11-9

  • Cat. No. CS-W021151
  • Molecule weight244.24
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid|CS-W021151

Structure of 1033713-11-9

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General Information

  • CAS No. 1033713-11-9
  • Cat. No. CS-W021151
  • Purity ≥97%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆N₂O₅
  • Molecular Weight 244.24
  • Synonym(s) None
  • SMILES O=C([C@H](CN1)N(C(OC(C)(C)C)=O)CC1=O)O

Description

This chiral piperazine derivative features a protected amine and a ketone-functionalized ring, enabling direct incorporation into peptide conjugates and bioactive molecule scaffolds. The tert-butoxycarbonyl group provides stability during synthesis, while the oxo and carboxylic acid moieties offer versatile handles for further derivatization under standard conditions.

Application

(S)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid serves as a versatile chiral building block in the synthesis of piperazine-based scaffolds. Its Boc-protected amine and carboxylic acid functionalities enable sequential derivatization, while the 5-oxo group facilitates nucleophilic addition and ring functionalization. The compound exhibits excellent bench stability and ease of purification, making it well-suited for medicinal chemistry campaigns requiring precise stereocontrol and functional group compatibility.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   95.94
  • LogP   -0.1935
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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