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CS-W001157 4
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N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine

  • CAS No. 1032759-30-0

  • Cat. No. CS-0091623
  • Purity≥98%
  • MDL No.MFCD07368238

*For research and further manufacturing use only, not for direct human use.

N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine|CS-0091623

Structure of 1032759-30-0

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General Information

  • CAS No. 1032759-30-0
  • Cat. No. CS-0091623
  • Purity ≥98%
  • MDL No. MFCD07368238
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀BN₃O₂
  • Molecular Weight 249.12
  • Synonym(s) 2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester
  • SMILES CC1(C)C(C)(C)OB(C2=CN=C(N(C)C)N=C2)O1

Synthesis

  • Route1

    References

    • Burger, Matthew T.; Knapp, Mark; Wagman, Allan; Ni, Zhi-Jie; Hendrickson, Thomas; Atallah, Gordana; Zhang, Yanchen; Frazier, Kelly; Verhagen, Joelle; Pfister, Keith; Ng, Simon; Smith, Aaron; Bartulis, Sarah; Merrit, Hanne; Weismann, Marion; Xin, Xiaohua; Haznedar, Joshua; Voliva, Charles F.; Iwanowicz, Ed; Pecchi, Sabina ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 34 - 38

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   47.48
  • LogP   0.8418
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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