Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl N-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]-N-methylcarbamate

  • CAS No. 1032758-87-4

  • Cat. No. CS-0022567
  • Purity≥97%
  • MDL No.MFCD09037484

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]-N-methylcarbamate|CS-0022567

Structure of 1032758-87-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1032758-87-4
  • Cat. No. CS-0022567
  • Purity ≥97%
  • MDL No. MFCD09037484
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₇BN₂O₄
  • Molecular Weight 334.22
  • Synonym(s) tert-Butyl methyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate
  • SMILES CN(C(OC(C)(C)C)=O)C1=NC=C(B2OC(C)(C)C(C)(C)O2)C=C1

Description

tert-Butyl N-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]-N-methylcarbamate features a boronate ester group appended to a pyridine scaffold, enabling efficient Suzuki-Miyaura coupling. The tert-butyl and methyl carbamate protections offer stability and selective deprotection, facilitating downstream functionalization in medicinal chemistry and materials synthesis under standard conditions.

Application

tert-Butyl N-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]-N-methylcarbamate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyridine scaffold enables access to functionalized heterocycles, while the tert-butyl carbamate group provides stability and orthogonal deprotection options. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of complex molecular architectures in medicinal chemistry and materials science workflows.

Synthesis

  • Route1

    References

    • WO2009/42607 A1, ; Page/Page column 84 ; WO 2009/042607 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.89
  • LogP   2.7521
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1032758-87-4 sigma1032758-87-4 manufacturer1032758-87-4 price1032758-87-4 structure1032758-87-4 SDSbuy 1032758-87-41032758-87-4 supplier1032758-87-4 uses1032758-87-4 molecular weightprice of 1032758-87-41032758-87-4 chemical name formula of 1032758-87-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label