Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

7-Bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine

  • CAS No. 1032650-41-1

  • Cat. No. CS-D0306
  • Purity≥98%
  • MDL No.MFCD11518977

*For research and further manufacturing use only, not for direct human use.

7-Bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine|CS-D0306

Structure of 1032650-41-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1032650-41-1
  • Cat. No. CS-D0306
  • Purity ≥98%
  • MDL No. MFCD11518977
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClN₃
  • Molecular Weight 232.47
  • Synonym(s) 5H-Pyrrolo[3,2-d]pyrimidine,7-bromo-4-chloro-
  • SMILES ClC1=C(NC=C2Br)C2=NC=N1

Description

7-Bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine is a heterocyclic building block featuring dual halogen substituents at electron-rich positions, enabling direct functionalization in cross-coupling reactions. This scaffold delivers high reactivity and stability under standard conditions, making it ideal for constructing complex purine analogs in medicinal chemistry and materials science applications.

Application

7-Bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine serves as a versatile building block for the synthesis of purine-based scaffolds. Its complementary halogenation pattern enables sequential cross-coupling reactions, facilitating efficient access to biologically relevant heterocycles. The compound exhibits excellent bench stability and compatibility with palladium-catalyzed transformations, making it well-suited for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2008/70507 A2, 2008 ; Location in patent: Page/Page column 153 ;
  • Route2

    References

    • Khoje, Abhijit Datta; Kulendrn, Aisvareya; Charnock, Colin; Wan, Baojie; Franzblau, Scott; Gundersen, Lise-Lotte Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 20 p. 7274 - 7282
  • Route3

    References

    • WO2011/113798 A2, ; WO 2011/113798 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.3738
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1032650-41-1 sigma1032650-41-1 manufacturer1032650-41-1 price1032650-41-1 structure1032650-41-1 SDSbuy 1032650-41-11032650-41-1 supplier1032650-41-1 uses1032650-41-1 molecular weightprice of 1032650-41-11032650-41-1 chemical name formula of 1032650-41-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label