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Structure of 1032528-06-5
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This tert-butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate integrates a boronate handle with a sterically hindered cyclobutyl scaffold, enabling robust Suzuki-Miyaura coupling under standard conditions. The protecting group remains stable during reaction setup and is readily removed post-functionalization, streamlining access to complex biaryl architectures.
tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. The cyclobutyl scaffold imparts conformational rigidity, enhancing stereochemical control in target molecule synthesis. The Bpin group enables high functional group tolerance and reliable coupling under mild conditions, while the tert-butyl carbamate offers stability and straightforward deprotection. This reagent facilitates efficient access to complex arylated cyclobutane motifs common in medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: