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Structure of 10325-70-9
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1-(Pyrimidin-5-yl)ethanone features a pyrimidine ring fused to an acetyl group, delivering a robust scaffold for medicinal chemistry. This electron-deficient heterocycle integrates readily into target molecules, enabling efficient access to bioactive compounds through nucleophilic substitution and cross-coupling reactions under standard conditions.
1-(Pyrimidin-5-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyrimidine ring and facile derivatization via enolization or nucleophilic substitution. Its ketone functionality provides a handle for reductive amination, Grignard addition, and transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability, simple purification by recrystallization, and compatibility with common protecting group strategies, making it a practical scaffold for heterocyclic compound synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: