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CS-W001157 4
Total: USD 88.00

4-Methoxyquinolin-3-amine

  • CAS No. 103040-77-3

  • Cat. No. CS-0499040
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methoxyquinolin-3-amine|CS-0499040

Structure of 103040-77-3

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General Information

  • CAS No. 103040-77-3
  • Cat. No. CS-0499040
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀N₂O
  • Molecular Weight 174.20
  • Synonym(s) None
  • SMILES NC1=C(OC)C2=CC=CC=C2N=C1

Description

4-Methoxyquinolin-3-amine features a quinolin-3-amine core decorated with a methoxy group at the 4-position, enhancing electron density and solubility. This scaffold integrates readily into pharmaceutical intermediates and functional materials, offering improved stability under standard conditions and facilitating downstream derivatization through its primary amine functionality.

Application

4-Methoxyquinolin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based pharmacophores. Its ortho-amino functionality facilitates palladium-catalyzed coupling reactions, while the methoxy group enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis and scaffold diversification in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   1.8256
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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