Lot numbers can be found on the outside label of a product:
(S)-Methyl 2,3-dihydroxypropanoate
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CAS No. 10303-88-5
- Cat. No. CS-W000794
- Purity≥96%
- MDL No.MFCD14636488
*For research and further manufacturing use only, not for direct human use.
Structure of 10303-88-5
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General Information
- CAS No. 10303-88-5
- Cat. No. CS-W000794
- Purity ≥96%
- MDL No. MFCD14636488
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₄H₈O₄
- Molecular Weight 120.10
- Synonym(s) Methyl L-(+)-glycerate
- SMILES COC(=O)[C@@H](O)CO
Description
(S)-Methyl 2,3-dihydroxypropanoate is a chiral diol ester featuring adjacent hydroxyl groups on a prochiral carbon backbone. This bench-stable derivative serves as a key building block in carbohydrate chemistry and asymmetric synthesis, where its defined stereochemistry enables selective transformations. The methyl ester moiety enhances solubility and stability under standard conditions, facilitating integration into complex synthetic sequences.
Application
(S)-Methyl 2,3-dihydroxypropanoate serves as a key chiral building block for the synthesis of bioactive molecules and natural product analogs. Its well-defined stereochemistry and two adjacent hydroxyl groups enable selective derivatization in glycosylation and phosphorylation reactions. The compound exhibits excellent bench stability, ease of purification, and compatibility with standard protecting group strategies, making it a reliable reagent in carbohydrate chemistry and medicinal intermediate development.
Synthesis
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Route1
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In-stock
60456-21-5 - ~99%
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In-stock
10303-88-5
References
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Bhatia, Suresh K.; Hajdu, Joseph Journal of Organic Chemistry, 1988 , vol. 53, # 21 p. 5034 - 5039
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Route2
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4538-50-5 - ~0%
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In-stock
18289-89-9 -
In-stock
10303-88-5
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4538-50-5
References
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Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N. Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
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Route3
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4538-50-5
- ~0%
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In-stock
10303-88-5
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4538-50-5
References
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Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N. Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 66.76
- LogP -1.4874
- H_Acceptors 4
- H_Donors 2
- Rotatable_Bonds 2
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Key Words
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