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Methyl 2,3-dihydroxypropanoate

  • CAS No. 615-34-9

  • Cat. No. CS-0454216
  • Purity≥95%
  • MDL No.MFCD16038665

*For research and further manufacturing use only, not for direct human use.

Methyl 2,3-dihydroxypropanoate|CS-0454216

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General Information

  • CAS No. 615-34-9
  • Cat. No. CS-0454216
  • Purity ≥95%
  • MDL No. MFCD16038665
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₄
  • Molecular Weight 120.10
  • Synonym(s) rac-2,3-dihydroxypropionic acid methyl ester
  • SMILES COC(=O)C(CO)O

Description

Methyl 2,3-dihydroxypropanoate is a diol-containing ester featuring two adjacent hydroxyl groups on a three-carbon chain, enabling versatile functionalization in carbohydrate chemistry and bioconjugation. This bench-stable derivative facilitates selective protection strategies and serves as a key intermediate in the synthesis of glycosidic analogs and chiral building blocks.

Application

Methyl 2,3-dihydroxypropanoate serves as a versatile diol-containing building block for the synthesis of carbohydrate mimetics and chiral intermediates. Its two adjacent hydroxyl groups enable selective protection and oxidation sequences, while the ester functionality supports downstream transformations such as reduction or nucleophilic displacement. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, facilitating integration into multi-step synthetic workflows.

Safety Information

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -1.4874
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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