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CS-W001157 4
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2-Chloroacetimidamide hydrochloride

  • CAS No. 10300-69-3

  • Cat. No. CS-W000829
  • Molecule weight128.99
  • Purity≥95%
  • MDL No.MFCD00053013

*For research and further manufacturing use only, not for direct human use.

2-Chloroacetimidamide hydrochloride|CS-W000829

Structure of 10300-69-3

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General Information

  • CAS No. 10300-69-3
  • Cat. No. CS-W000829
  • Purity ≥95%
  • MDL No. MFCD00053013
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₆Cl₂N₂
  • Molecular Weight 128.99
  • Synonym(s) 2-chloroacetamidine monohydrochloride
  • SMILES Cl.NC(=N)CCl

Description

2-Chloroacetimidamide hydrochloride offers a stable, moisture-tolerant platform for imine-based transformations. This bench-stable reagent integrates readily into synthetic sequences requiring nitrogen transfer or electrophilic amidation. The chloride-bearing imidamide moiety enables efficient coupling with nucleophiles under mild conditions, streamlining access to functionalized heterocycles and amine derivatives in medicinal chemistry workflows.

Application

2-Chloroacetimidamide hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling the efficient construction of nitrogen-containing heterocycles and functionalized imidates. Its stability under standard bench conditions and compatibility with diverse reaction environments facilitate straightforward incorporation into complex molecular architectures. The compound functions as a key reagent in the synthesis of medicinally relevant scaffolds, particularly those requiring controlled amidine or guanidine formation.

Synthesis

  • Route1
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      107-14-2
    • ~%
    • In-stock
      2-Chloroacetimidamide hydrochloride|CS-W000829
      10300-69-3

    References

    • US4328029 A1, ;
  • Route2
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      41264-52-2
    • ~%
    • In-stock
      2-Chloroacetimidamide hydrochloride|CS-W000829
      10300-69-3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 433 - 436

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.87
  • LogP   0.58297
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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