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CS-W001157 4
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5H-pyrrolo[3,2-d]pyrimidine-4-carboxylic acid

  • CAS No. 1029144-15-7

  • Cat. No. CS-0050463
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5H-pyrrolo[3,2-d]pyrimidine-4-carboxylic acid|CS-0050463

Structure of 1029144-15-7

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General Information

  • CAS No. 1029144-15-7
  • Cat. No. CS-0050463
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) None
  • SMILES OC(=O)C1=NC=NC2=C1NC=C2

Description

5H-Pyrrolo[3,2-d]pyrimidine-4-carboxylic acid integrates a fused heterocyclic core with a carboxylic acid handle, enabling direct conjugation in medicinal chemistry. This electron-deficient scaffold supports efficient derivatization and serves as a key building block for kinase inhibitors and nucleoside analogs.

Application

5H-Pyrrolo[3,2-d]pyrimidine-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its carboxylic acid functionality enables straightforward derivatization via amide formation, esterification, or coupling reactions. The fused pyrrolopyrimidine core exhibits favorable stability under standard reaction conditions and demonstrates compatibility with diverse functional groups, facilitating its use in the synthesis of kinase inhibitors and other bioactive scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.6561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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