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Structure of 1027818-88-7
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4-Chloro-5-iodo-2-(trifluoromethyl)pyridine features a trifluoromethyl group flanked by chlorine and iodine substituents on a pyridine core, enabling selective cross-coupling reactions. The electron-deficient aromatic framework supports palladium-catalyzed transformations, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity in medicinal chemistry applications.
4-Chloro-5-iodo-2-(trifluoromethyl)pyridine serves as a versatile heterocyclic building block for Suzuki-Miyaura and Sonogashira coupling reactions, enabling efficient construction of biaryl and alkynyl scaffolds. The orthogonal reactivity of the chloro and iodo substituents allows sequential functionalization under mild conditions. Bench-stable and compatible with diverse reaction environments, it facilitates the synthesis of complex trifluoromethylated pyridine derivatives relevant to pharmaceutical and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: