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CS-W001157 4
Total: USD 88.00

(8-Methylquinolin-5-yl)boronic acid

  • CAS No. 1025010-58-5

  • Cat. No. CS-0175786
  • Molecule weight187.01
  • Purity≥97%
  • MDL No.MFCD05256435

*For research and further manufacturing use only, not for direct human use.

(8-Methylquinolin-5-yl)boronic acid|CS-0175786

Structure of 1025010-58-5

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General Information

  • CAS No. 1025010-58-5
  • Cat. No. CS-0175786
  • Purity ≥97%
  • MDL No. MFCD05256435
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀BNO₂
  • Molecular Weight 187.01
  • Synonym(s) 8-Methylquinoline-5-boronic acid
  • SMILES CC1=C2C(C=CC=N2)=C(B(O)O)C=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura couplings, delivering functionalized quinoline scaffolds with high efficiency. The methyl group enhances electron density at the aromatic ring, improving reactivity and stability under standard conditions.

Application

(8-Methylquinolin-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The quinoline core provides enhanced stability and favorable electronic properties, while the boronic acid group offers excellent functional group tolerance and ease of purification. Its bench-stable nature and compatibility with diverse reaction partners make it a practical choice for medicinal chemistry and materials synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   0.22302
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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