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Structure of 1022931-73-2
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tert-Butyl 3-(trifluoromethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate features a trifluoromethyl-substituted pyrazolopyridine core with a bench-stable tert-butyl ester handle. This electron-deficient heterocycle integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active agents. The dihydro-pyrazole scaffold provides structural rigidity and enhanced metabolic stability.
tert-Butyl 3-(trifluoromethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient access to pyrazolopyridine scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the tert-butyl ester facilitates straightforward deprotection under mild acidic conditions. The dihydro-pyrazolo[4,3-c]pyridine core exhibits predictable reactivity in cross-coupling and functionalization reactions, supporting its use in medicinal chemistry campaigns requiring robust, bench-stable intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: