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CS-W001157 4
Total: USD 88.00

2-Bromoimidazo[5,1-b]thiazole

  • CAS No. 713107-45-0

  • Cat. No. CS-0620461
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromoimidazo[5,1-b]thiazole|CS-0620461

Structure of 713107-45-0

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General Information

  • CAS No. 713107-45-0
  • Cat. No. CS-0620461
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrN₂S
  • Molecular Weight 203.06
  • Synonym(s) None
  • SMILES BrC1=CN2C(S1)=CN=C2

Description

2-Bromoimidazo[5,1-b]thiazole is a heterocyclic bromide featuring a fused imidazole-thiazole core with high electrophilic character at the bromine site. This scaffold integrates readily into C–N and C–C coupling processes, offering enhanced stability under standard conditions. Its electron-deficient ring system facilitates selective functionalization in synthetic sequences.

Application

2-Bromoimidazo[5,1-b]thiazole serves as a versatile heterocyclic building block for constructing biologically relevant scaffolds. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the assembly of complex molecular architectures. The imidazo[5,1-b]thiazole core exhibits good bench stability and functional group tolerance, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   17.3
  • LogP   2.1583
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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