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Structure of 1019016-66-0
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6-Bromo-4-chloro-8-fluoroquinoline serves as a critical building block in the synthesis of advanced pharmaceutical intermediates and functional materials. The strategic placement of bromo, chloro, and fluoro substituents imparts enhanced reactivity and electronic tuning, enabling efficient coupling reactions under standard conditions. This electron-deficient quinoline derivative exhibits excellent stability and solubility in organic solvents, facilitating straightforward incorporation into complex molecular architectures.
6-Bromo-4-chloro-8-fluoroquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. The strategically positioned halogen atoms (Br, Cl, F) offer orthogonal reactivity for sequential derivatization, while the quinoline core provides inherent stability and π-conjugation. Its bench-stable solid form facilitates handling and purification, making it ideal for modular synthesis of pharmaceutical candidates and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: