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7-Deaza-2′-deoxyguanosine 5′-triphosphate

  • CAS No. 101515-08-6

  • Cat. No. CS-0256324
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Deaza-2′-deoxyguanosine 5′-triphosphate|CS-0256324

Structure of 101515-08-6

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General Information

  • CAS No. 101515-08-6
  • Cat. No. CS-0256324
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₄O₁₃P₃
  • Molecular Weight 506.19
  • Synonym(s) 7-Deaza-2'-dGTP
  • SMILES O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3C=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Description

Inhibiting telomerase activity via competitive incorporation into elongating DNA strands, 7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt (CAS 101515-08-6) disrupts telomere maintenance in proliferative cells.

Application

7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt (CAS 101515-08-6) enables efficient DNA polymerase activity across platforms, including Taq, by serving as a direct analog to dGTP in chain elongation. It reduces gel compression artifacts during sequencing. This substitution enhances PCR yield in GC-rich templates by destabilizing secondary structures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H371
Precautionary Statements : P260-P264-P270-P405-P501

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Computational Chemistry Data

  • TPSA   265.98
  • LogP   -0.7015
  • H_Acceptors   12
  • H_Donors   7
  • Rotatable_Bonds   8

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