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CS-W001157 4
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2'-Deoxyuridine 5'-monophosphate disodium

  • CAS No. 42155-08-8

  • Cat. No. CS-W011858
  • Purity≥98%
  • MDL No.MFCD00065282

*For research and further manufacturing use only, not for direct human use.

2'-Deoxyuridine 5'-monophosphate disodium|CS-W011858

Structure of 42155-08-8

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General Information

  • CAS No. 42155-08-8
  • Cat. No. CS-W011858
  • Purity ≥98%
  • MDL No. MFCD00065282
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N₂Na₂O₈P
  • Molecular Weight 352.15
  • Synonym(s) dUMP (disodium)
  • SMILES O[C@H]1C[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O[Na])(O[Na])=O

Description

In nucleotide synthesis pathways, 2′-Deoxyuridine 5′-monophosphate disodium salt (CAS 42155-08-8) undergoes enzymatic methylation via thymidylate synthase to yield deoxythymidine monophosphate, a critical precursor for DNA replication.

Application

2′-Deoxyuridine 5′-monophosphate disodium salt (CAS 42155-08-8) drives de novo dTMP synthesis by serving as the essential substrate for thymidylate synthetase in DNA replication. It powers cancer drug screening. Researchers rely on this compound to evaluate dUMP analogues, refining targeted chemotherapy strategies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   129.08
  • LogP   -1.4901
  • H_Acceptors   9
  • H_Donors   2
  • Rotatable_Bonds   6

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