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Structure of 10123-62-3
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Diethyl (2-cyanoethyl)phosphonate features a cyanoethyl group that enables efficient conjugate addition reactions. This phosphonate ester delivers high functional group tolerance and stability under standard conditions, facilitating direct incorporation into complex molecular architectures. The electron-deficient nitrile moiety enhances reactivity in nucleophilic transformations, supporting streamlined synthesis of phosphorylated analogs.
Diethyl (2-cyanoethyl)phosphonate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to phosphonate-containing scaffolds via Pudovik or Michael-type additions. Its cyano group facilitates subsequent transformations such as hydrolysis, reduction, or cyclization, while the phosphonate moiety supports Stetter, Horner–Wadsworth–Emmons, and related olefination reactions. The compound exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for use in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: