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CS-W001157 4
Total: USD 88.00

(6-Cyanopyridin-3-yl)boronic acid

  • CAS No. 1011722-07-8

  • Cat. No. CS-W004927
  • Purity≥98%
  • MDL No.MFCD10696633

*For research and further manufacturing use only, not for direct human use.

(6-Cyanopyridin-3-yl)boronic acid|CS-W004927

Structure of 1011722-07-8

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General Information

  • CAS No. 1011722-07-8
  • Cat. No. CS-W004927
  • Purity ≥98%
  • MDL No. MFCD10696633
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BN₂O₂
  • Molecular Weight 147.93
  • Synonym(s) (6-Cyanopyridin-3-yl)boronicacid
  • SMILES N#CC1=CC=C(B(O)O)C=N1

Description

This boronate moiety features a cyanopyridine handle enabling direct functionalization in cross-coupling reactions. The electron-deficient pyridine ring enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

(6-Cyanopyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its cyano group enhances electronic polarization, improving reactivity while maintaining bench stability and compatibility with diverse functional groups. The boronic acid moiety facilitates straightforward purification and is compatible with standard aqueous workups, making it well-suited for iterative synthesis in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   77.14
  • LogP   -1.36692
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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