Lot numbers can be found on the outside label of a product:
(6-Chloropyridazin-3-yl)methanol
-
CAS No. 1011487-94-7
- Cat. No. CS-0053132
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 1011487-94-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1011487-94-7
- Cat. No. CS-0053132
- Purity ≥97%
- MDL No. None
- Storage -20°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₅ClN₂O
- Molecular Weight 144.56
- Synonym(s) 6-Chloropyridazine-3-methanol
- SMILES OCC1=NN=C(Cl)C=C1
Description
(6-Chloropyridazin-3-yl)methanol features a chlorinated pyridazinone core with a reactive hydroxymethyl group, enabling direct functionalization in medicinal chemistry. This bench-stable scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability in drug discovery applications.
Application
(6-Chloropyridazin-3-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridazinone derivatives through nucleophilic substitution and subsequent functionalization. Its chloro group facilitates palladium-catalyzed coupling reactions, while the pendant alcohol supports derivatization via esterification or ether formation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for use in iterative synthesis campaigns targeting bioactive heterocycles.
Synthesis
-
Route1
-
6531-04-0 - ~%
-
In-stock
1011487-94-7
References
-
Bayer Schering Pharma Aktiengesellschaft Patent: US2010/93728 A1, 2010 ; Location in patent: Page/Page column 18 ; US 20100093728 A1
-
-
Route2
-
In-stock
65202-50-8 - ~%
-
In-stock
1011487-94-7
References
-
MITSUBISHI TANABE PHARMA CORPORATION; SAKURAI, Osamu; SARUTA, Kunio; HAYASHI, Norimitsu; GOI, Takashi; MOROKUMA, Kenji; TSUJISHIMA, Hidekazu; SAWAMOTO, Hiroaki; SHITAMA, Hiroaki; IMASHIRO, Ritsuo Patent: WO2012/81736 A1, 2012 ; Location in patent: Page/Page column 82 ; WO 2012/081736 A1
-
-
Route3
-
In-stock
303085-53-2 - ~%
-
In-stock
1011487-94-7
References
-
MERCK and CO., INC. Patent: WO2009/134668 A2, 2009 ; Location in patent: Page/Page column 30 ; WO 2009/134668 A2
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.01
- LogP 0.6223
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- (6-Chloropyridazin-3-yl)methanol sigma(6-Chloropyridazin-3-yl)methanol manufacturer(6-Chloropyridazin-3-yl)methanol price(6-Chloropyridazin-3-yl)methanol structure(6-Chloropyridazin-3-yl)methanol SDSbuy (6-Chloropyridazin-3-yl)methanol(6-Chloropyridazin-3-yl)methanol supplier(6-Chloropyridazin-3-yl)methanol uses(6-Chloropyridazin-3-yl)methanol molecular weightprice of (6-Chloropyridazin-3-yl)methanol(6-Chloropyridazin-3-yl)methanol chemical name formula of (6-Chloropyridazin-3-yl)methanol