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(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol

  • CAS No. 1011465-19-2

  • Cat. No. CS-0087950
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol|CS-0087950

Structure of 1011465-19-2

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General Information

  • CAS No. 1011465-19-2
  • Cat. No. CS-0087950
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₄H₃₄O₄
  • Molecular Weight 506.63
  • Synonym(s) None
  • SMILES OC(C(C1=CC=C(OC)C=C1)=C2)=C(C3=C(CCCC4)C4=CC(C5=CC=C(OC)C=C5)=C3O)C6=C2CCCC6

Description

(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol features a chiral binaphthyl scaffold with two electron-rich methoxy-substituted aryl groups and hydroxyl functionalities at the 2,2' positions. This bench-stable, moisture-tolerant diol serves as a stereocontrolled building block in asymmetric synthesis, particularly for ligands and catalysts requiring defined axial chirality and enhanced solubility in polar solvents.

Application

(R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol serves as a chiral scaffold for asymmetric synthesis, enabling stereocontrolled transformations via its rigid binaphthyl core and diol functionality. The 4-methoxyphenyl substituents enhance solubility and stability, while the octahydro modification reduces aromaticity to favor functional group manipulation. This compound functions effectively in transition-metal-catalyzed reactions and serves as a building block for ligands and catalysts in enantioselective processes.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   7.8736
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

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