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Structure of 100927-10-4
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(R)-tert-Butyl (1-aminopropan-2-yl)carbamate is a chiral building block featuring a stereodefined secondary amine and a robust tert-butyloxycarbonyl (Boc) protecting group. This configuration enables selective coupling in asymmetric synthesis, particularly for peptidomimetics and bioactive intermediates. The molecule exhibits excellent stability under standard bench conditions and facilitates straightforward deprotection to reveal the free amine.
(R)-tert-Butyl (1-aminopropan-2-yl)carbamate serves as a chiral, bench-stable amino protecting group precursor for the synthesis of (R)-configured amino alcohols and β-amino acid derivatives. It facilitates efficient N–C bond formation in peptide coupling and asymmetric synthesis, with high functional group tolerance and straightforward deprotection under mild acidic conditions. Its robustness and stereochemical integrity make it a reliable building block for complex molecular scaffolds in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: