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Structure of 1008304-87-7
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4-Fluoro-3-(trifluoromethyl)benzenesulfonamide features a trifluoromethyl group flanking a fluorine-substituted aromatic ring, delivering enhanced electron-withdrawing character and metabolic stability. This sulfonamide integrates readily into bioactive scaffolds, offering improved solubility and binding affinity in medicinal chemistry applications.
4-Fluoro-3-(trifluoromethyl)benzenesulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the sulfonamide moiety provides strong hydrogen-bonding capacity and favorable pharmacokinetic properties. The compound exhibits excellent bench stability, tolerates a broad range of reaction conditions, and facilitates efficient purification via crystallization or chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: