Lot numbers can be found on the outside label of a product:
Methyl 2,2-dimethoxypropanoate
-
CAS No. 10076-48-9
- Cat. No. CS-0094869
- Purity≥98%
- MDL No.MFCD00048066
*For research and further manufacturing use only, not for direct human use.
Structure of 10076-48-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 10076-48-9
- Cat. No. CS-0094869
- Purity ≥98%
- MDL No. MFCD00048066
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₁₂O₄
- Molecular Weight 148.16
- Synonym(s) 2,2-Dimethoxypropionic Acid Methyl Ester
- SMILES CC(OC)(OC)C(OC)=O
Description
Methyl 2,2-dimethoxypropanoate is a bench-stable, moisture-tolerant acetal ester featuring a geminal dimethoxy group that stabilizes adjacent carbonyl reactivity. This protected α-carbonyl synthon integrates readily into multistep synthesis, enabling controlled release of reactive intermediates under mild acidic conditions.
Application
Methyl 2,2-dimethoxypropanoate serves as a stable, bench-ready acylating agent that facilitates efficient formation of ketones via nucleophilic addition followed by hydrolysis. Its dimethoxyacetyl moiety enables reliable carbon–carbon bond construction in multistep syntheses, particularly in the preparation of α-hydroxy and α-amino carbonyl derivatives. The compound exhibits excellent functional group tolerance and simplifies purification due to its crystalline nature and predictable reaction profile.
Synthesis
-
Route1
-
In-stock
600-22-6 -
149-73-5 - ~98%
-
In-stock
10076-48-9
References
-
Wenkert, Ernest; Alonso, Miguel E.; Buckwalter, Brian L.; Sanchez, Eduardo L. Journal of the American Chemical Society, 1983 , vol. 105, # 7 p. 2021 - 2029
-
-
Route2
-
In-stock
600-22-6
-
149-73-5
- ~91%
-
107-31-3
-
In-stock
10076-48-9
References
-
KANSAI PAINT CO., LTD. Patent: WO2006/35915 A1, 2006 ; Location in patent: Page/Page column 49-50 ;
-
-
Route3
-
67-56-1
-
In-stock
600-22-6
-
149-73-5
- ~63%
-
In-stock
10076-48-9
References
-
SCHERING CORPORATION Patent: WO2009/105500 A1, 2009 ; Location in patent: Page/Page column 215 ; WO 2009/105500 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 44.76
- LogP 0.1684
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 2,2-dimethoxypropanoate sigmaMethyl 2,2-dimethoxypropanoate manufacturerMethyl 2,2-dimethoxypropanoate priceMethyl 2,2-dimethoxypropanoate structureMethyl 2,2-dimethoxypropanoate SDSbuy Methyl 2,2-dimethoxypropanoateMethyl 2,2-dimethoxypropanoate supplierMethyl 2,2-dimethoxypropanoate usesMethyl 2,2-dimethoxypropanoate molecular weightprice of Methyl 2,2-dimethoxypropanoateMethyl 2,2-dimethoxypropanoate chemical name formula of Methyl 2,2-dimethoxypropanoate